English name: Florfenicol Powder
Properties: This product is white or almost white powder.
Pharmacological action: pharmacodynamics, florfenicol is a broad-spectrum antibiotic of amide alcohols, a bacteriostatic agent, it acts by binding to the 50S subunit of the ribosome to inhibit the synthesis of bacterial protein. It has strong antibacterial activity against a variety of gram-positive and gram-negative bacteria. Pasteurella hemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae are highly sensitive to florfenicol. The antibacterial activity of florfenicol against many microorganisms in vitro is similar to or stronger than that of thiamphenicol. Some bacteria resistant to amide alcohols due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be resistant to fluorobenzene. Nico is sensitive. It is mainly used for bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as respiratory diseases of cattle and pigs caused by Pasteurella hemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae. Salmonella caused by typhoid fever and paratyphoid fever, chicken cholera, chicken pullorum, colibacillosis, etc.; fish bacterial sepsis caused by fish pasteurella, vibrio, Staphylococcus aureus, hydrophila, enteritis bacteria, etc. , Enteritis, red skin disease, etc.
Pharmacokinetics The oral administration of florfenicol is quickly absorbed, and the therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached within 1-3 hours. The bioavailability is over 80%. Florfenicol is widely distributed in animals and can penetrate the blood-brain barrier. It is mainly excreted in urine in its original form, and a small amount is excreted in feces.
product name: Florfenicol Powder
Main ingredients: Florfenicol
product status: powder
Scope of use: breeding animals.
Packing: 100g/bag
Specification: 20%
Withdrawal period: 20 days for pigs, 5 days for chickens
Usage: Oral : every 1kg body weight, 0.1-0.15g for pigs and chickens, twice a day for 3-5 days; fish, 50-75mg, once a day for 3 to 5 days.
Validity period: 2 years
Florfenicol Powder application range:
medicine interactions:
(1) Macrolides and lincosamides have the same target of action as this product, both of which are combined with the 50S subunit of the bacterial ribosome, and can produce mutual antagonism when used in combination.
(2) It may antagonize the bactericidal activity of penicillins or aminoglycoside drugs, but it has not been proven in animals.
Role and use: Amido alcohol antibiotics. Used for bacterial diseases caused by Pasteurella and Escherichia coli.
Adverse reactions:
(1) This product has a certain immunosuppressive effect when used higher than the recommended dose.
(2) It has embryo toxicity, and it should be used with caution for livestock during pregnancy and lactation.
Precautions:
(1) Banned during laying hens.
(2) Animals with severely impaired immune function during the vaccination period are prohibited.
(3) Animals with renal insufficiency need to appropriately reduce the dose or extend the interval between administrations.
